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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC24A
All Species:
21.21
Human Site:
S250
Identified Species:
35.9
UniProt:
O95486
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95486
NP_068817.1
1093
119749
S250
V
N
Q
E
G
I
T
S
N
T
N
N
G
S
M
Chimpanzee
Pan troglodytes
XP_527165
1093
119711
S250
V
N
Q
E
G
I
T
S
N
T
N
N
G
S
M
Rhesus Macaque
Macaca mulatta
XP_001109620
1093
119674
S250
V
N
Q
E
G
I
T
S
T
A
N
N
G
S
M
Dog
Lupus familis
XP_850736
1100
120445
S257
V
N
Q
E
G
I
A
S
N
T
N
N
G
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q3U2P1
1090
118764
S248
V
N
Q
E
G
I
T
S
N
A
N
N
G
S
T
Rat
Rattus norvegicus
NP_001099250
1089
118849
T247
A
V
N
Q
E
G
I
T
S
N
A
N
T
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510651
1234
134485
A356
T
N
P
E
G
D
V
A
S
T
A
N
N
G
S
Chicken
Gallus gallus
XP_414630
1100
120006
S257
N
Q
E
G
D
A
T
S
A
A
G
D
G
S
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001340708
1097
118527
A250
V
P
P
P
P
T
G
A
H
S
D
A
G
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394884
843
95632
P51
G
Y
N
K
L
W
Y
P
N
Q
L
P
N
S
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784354
1353
146633
I384
I
N
P
F
V
A
F
I
D
Q
R
R
W
R
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SFU0
1038
113942
G243
S
Y
P
P
H
T
G
G
F
A
Q
R
P
N
M
Baker's Yeast
Sacchar. cerevisiae
P40482
926
103617
P134
A
M
G
Q
N
M
R
P
M
N
Q
L
Y
P
I
Red Bread Mold
Neurospora crassa
Q7S4P3
950
103512
S158
G
I
T
A
G
I
Q
S
M
G
F
G
G
Q
P
Conservation
Percent
Protein Identity:
100
99.4
97.7
92.1
N.A.
88.3
88.2
N.A.
69.1
74
N.A.
59.5
N.A.
N.A.
44.7
N.A.
28.7
Protein Similarity:
100
99.8
98.2
94.2
N.A.
92.4
92
N.A.
76.2
83
N.A.
71.4
N.A.
N.A.
59.4
N.A.
43
P-Site Identity:
100
100
86.6
93.3
N.A.
86.6
6.6
N.A.
33.3
26.6
N.A.
13.3
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
100
100
86.6
93.3
N.A.
86.6
26.6
N.A.
46.6
46.6
N.A.
40
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
29.7
31.7
Protein Similarity:
N.A.
N.A.
N.A.
53.5
48.2
49.7
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
8
0
15
8
15
8
29
15
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
8
8
0
0
8
0
8
8
0
0
0
% D
% Glu:
0
0
8
43
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
8
0
8
0
8
0
0
0
0
% F
% Gly:
15
0
8
8
50
8
15
8
0
8
8
8
58
15
0
% G
% His:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
43
8
8
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% L
% Met:
0
8
0
0
0
8
0
0
15
0
0
0
0
0
43
% M
% Asn:
8
50
15
0
8
0
0
0
36
15
36
50
15
8
0
% N
% Pro:
0
8
29
15
8
0
0
15
0
0
0
8
8
15
8
% P
% Gln:
0
8
36
15
0
0
8
0
0
15
15
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
8
15
0
8
0
% R
% Ser:
8
0
0
0
0
0
0
50
15
8
0
0
0
50
15
% S
% Thr:
8
0
8
0
0
15
36
8
8
29
0
0
8
0
8
% T
% Val:
43
8
0
0
8
0
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
15
0
0
0
0
8
0
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _